Tuesday, 1 May 2018

Blood cancer treatments in India - 1 / Acute Myeloid Leukemia (AML) - CMCS Health.

Medical Treatments in India with Best Doctors in Best Indian Hospitals.




Leukemia or Leukemia can be classified as group of cancers that originate in Bone marrow and are characterized with abnormally high number of white blood cells . These while blood cells are not fully developed WBCs and are termed as blasts or leukemia cells. These abnormal WBC suppress the production of normal blood cells that ultimately culminate in anemia and other symptoms.

What are various Types of Leukemia :

Leukemia or Blood Cancers can be classified into sub-types depending on the time of disease progression and type of cell that has undergone the genetic mutation.
When the cells are multiplied rapidly and the onset of disease is fast it is termed as acute whereas when the onset of disease is slow and the symptoms are barely noticeable it is called chronic.
When the genetic mutation occurs in the myeloid cells the leukemia is termed as Myelogenous Leukemia whereas when the lymphocytes undergo the genetic mutation the leukemia is called lymphocytic leukemia. Depending on these characteristics disease Leukemia can be classified in four major sub-types.

  • Acute Myelogenous Leukemia (AML)
  • Acute Lymphocytic Leukemia  (ALL)
  • Chronic Myelogenous Leukemia (CML)
  • Chronic Lymphocytic Leukemia (CLL )


In this series about various Blood Cancers ( Leukemias) and their treatment in India ,The first one is about Acute Myelogenous Leukemia ( AML).



Acute Myelogenous Leukemia (AML): 

AML is the mutation in immature blood cells on the myeloid lines. In AML Patients there is an over production of immature WBCs ( Blasts) ,which occupy the majority of Bone marrow and hinders the production of normal blood cells. As there is reduced production of normal blood cells ,AML patient will be prone to anemia , bruising and bleeding easily  and recurrent infections. The leukemic blast cells eventually overflow into blood stream and can get accumulated in other organs like liver,spleen,lymph nodes,central nervous system ( spinal chord and brain) and testicles.

Signs and Symptoms of AML:



What are Risk factors associated with AML :

Following factors are identified as higher risk for developing AML.

1.Smoking:

   Smoking is the only proven life style related factor for AML. Researchers attribute about 20% of AML cases to smoking tobacco.

2. Radiation: 

   High dose radiation exposure (As in case of a survivor of Atomic bomb blast or nuclear reactor accident) are at a higher risk of developing AML most often about 6 to 8 years of exposure. Radiation treatment for cancer also increases the risk of AML. The risk varies with the amount of radiation and the treated body part.
Continuous Low level radiation exposure like from X Ray machines and CT scan machines are also linked to risk of developing AML in foetus in formative years , that is the reason doctors practice to limit the exposure in children and pregnant women.

3.Chemical Exposure:

 Long term exposure to certain chemicals like Benzene is considered a risk factor for     AML. Benzene is a solvent used in the rubber industry, oil refineries,chemical plants, shoe manufacturing, and petroleum-related industries, and is also found in cigarette smoke, gasoline and motor vehicle exhaust, and some glues, cleaning products,detergents, art supplies, and paints.Unconfirmed researches also link heavy exposure to formaldehyde as a risk factor for AML.

4. Chemotherapy Drugs:

    People who have undergone chemotherapy with medicines like cyclophosphamide,procarbazine,
    chlorambucil,melphelan,busalphan,cisplatin,carboplatin,epirubicin and doxorubicin for treatment        of other cancers are also at a higher risk of acquiring AML later on.

5. Certain Blood Disorders:

    Certain blood disorders are also associated with increased risk of AML. Chronic                                  Myeloproliferative disorders put the sufferer at a higher risk for AML.
    Myelodysplastic syndrome (MDS) may develop into AML if not treated in time.

6.Genetic Disorders:

People born with certain genetic disorders are at a higher risk of developing AML. Genetic                disorders like Fanconi Anemia,Bloom Syndrome,Kostmann syndrome,Neurofibromatosis Type 1,Diamond-Blackfan Anemia, Le Fraumeni Syndrome increases the risk of AML.

7.Age and Gender:

Although AML can occur at any age but men above 50 are at a higher risk of AML. AML is more common in men than women.


HOW AML is diagnosed ?

Once you approach a doctor for your sickness and symptoms usually after an abnormal CBC (Complete Blood count ),doctor will take your family history , do a physical examination paying special attention to your eyes,mouth,skin,lymph nodes,liver ,spleen and will look for areas of bleeding and bruising or any possible infection. Your risk of Having a Leukemia will also be assessed by the doctor. If your doctor suspects your sickness to be leukemia,he will order a CBC and peripheral blood smear.
Depending on these test reports your doctor may refer you to a Hematologist ( An specialists of blood diseases).
At CMCS Health ,we are associated with well qualified and experienced Hematologists for best treatment of our global guests.
A hematologist will have to diagnose your disease ,staging of disease and suitable treatment options if you are suffering from AML.
The Following tests and scans will be recommended by your Hematologist for confirmation of diagnosis,staging and deciding about treatment course.

Bone Marrow Tests: 

The samples for the two tests are usually taken from the back of pelvic ( hip) bone, which are carried out simultaneously.These two tests are :

  • Bone Marrow Biopsy
  • Bone marrow aspiration
The other tests and screenings are:
  • CSF ( Cerebro-spinal fluid) samples are collected through a Lumber puncture or spinal tap if your doctor suspects that the disease may have spread to brain and spinal chord.It is also done for administering the chemotherapy drugs either to prevent the leukemic cell invasion of CSF or treat the spread of disease to brain and spinal chord.
  • Routine microscopic examination 
  • Cytochemistry
  • Flow cytometry
  • Florescent in situ hybridization ( FISH)
  • Polymerase chain reaction ( PCR )
There may be other imaging tests recommended by your treating doctor ,not for diagnosing AML but for staging and gauging the spread of disease. These tests may include chest X rays,CT scan ,CT guided needle biopsy,PET/CT, MRI and Ultrasound.

Treatment Of AML:

Treatment of AML is mainly chemotherapy , sometimes chemo is given along with a targeted therapy drug, Bone Marrow transplant or Stem cell transplant are also used for patients who are in higher risk of relapse of disease.In special circumstances Radiation therapy and surgery is also combined with Chemotherapy.
Although AML usually affects ageing adults but it may also affects people pf any age and children too. For treatment of pediatric AML at CMCS Health we are associated with best Pediatrics BMT specialists and hemato Oncologists.

For Any Queries regarding medical treatment of Leukemia or Blood Cancers in India with Best Indian Specialist Hematologists at well equipped Indian Hospitals please contact at:









Monday, 2 April 2018

Knee joint and Hip Joint replacement surgery in India for Foreign Patients | CMCS Health.


India is the Global Joint Replacement Surgeries Hub for International Patients.

Patients from many countries visit India for cost-effective Orthopedic Surgeries. Joint Replacement Programs at the Top Orthopedic Surgery centers in India are the most sought-after Medical Treatments in India among Foreign Patients. Patients from Tanzania, Kenya, Nigeria, Zimbabwe, Zambia, Uganda, and Cameroon prefer India for Knee Joint and Hip Joint Replacement Surgeries in India. Even in developed countries Patients like Australia, France, and even the United Kingdom and the United States of America prefer to have Joint Replacement surgeries in India. 

Why do Foreign Patients prefer India for Knee Joint Replacement and Hip Joint Replacement Surgeries?

Many countries in the world are offering Joint Replacement surgeries for the Global Patients. Spain, Poland, India, Israel, Singapore, Thailand, Turkey, and Egypt are the Major medical tourism destinations among foreign patients for Knee Joint and Hip Joint Replacement Surgery. India has emerged as the top Medical Tourism Destination among foreign patients for affordable and truly world-class Joint Replacement Surgeries. The Following factors tilt the balance in favor of India when it comes to Joint replacement Surgeries among Foreign patients. 

Best Medical Tourism Assistance in India for Foreign Patients seeking Joint Replacement.

The Medical Tourism segment in India is quite robust and well organized. Many Medical tourism provider agencies in India offer the best services to international patients seeking medical treatments in India. They assist the patients and their medical attendants in all aspects of Medical Treatment and related logistics. The Leading Medical Tourism Provider Agency in India has so far assisted more than 10'000 International patients for their Medical Treatments in India.



The Ease of Access to Top Joint Replacement Centers in India

Indian Government has observed the potential and growth opportunities in Medical Tourism in India. It has taken the initiative in making the Medical Visa process easy (both regular/paper Medical Visa) and starting the E-Medical Visa facilities for the citizens of many countries visiting India for Medical Purposes. An e-Medical Visa is completely hassle-free and does not require the patient and their medical attendants to be physically present at the respective Indian High Commissions and Indian Consulates for granting of Indian e-Medical Visa. An E-medical Visa allows foreigners to stay in India for Medical treatment for up to 60 days. This is the sufficient duration required for even bilateral knee and Hip Joint replacement surgery. Important Links for Foreigners Seeking Knee and Hip Joint Replacement in India:

The Competency and Expertise of Indian Orthopedic Surgeons

The Reputation of Indian Joint Replacement Specialist Orthopedic Surgeons is very well-acknowledged and appreciated by patients from all across the world. Indian Orthopedic Surgeons are specially trained in Minimally Invasive (MIS) Arthroplasties and Robotic Joint replacement surgeries. CMCS Health, the Best Medical Tourism Company in India is associated with the Best Joint Replacement Surgeons in India for low-cost yet highly successful Joint Replacement Surgeries.

Top Joint Replacement Orthopedic Centers in India

The Top Orthopedics and Joint Replacement Centers in India are having the state of the art infrastructure and Modular Operation Theaters that are well-equipped with the latest technologies and safety protocols for Safe Joint Replacement Surgery for International Patients. The thrust is to provide a complete infection-free atmosphere in both the Operation Theaters and the Patient recovery rooms for Joint replacement patients.

Latest Cutting-Edge Technologies for Joint Replacement Surgery

The Best Indian Joint Replacement Surgeons and the Top Orthopedic and Joint Replacement Centers in India use Cutting-Edge technologies for Joint Replacement Surgery for Foreign Patients. Robotic Joint Replacement with Mako SmartRobotics and NAV3 Computer Navigation offers many benefits over conventional Joint Replacement Surgeries:
  • The accurate and precise positioning of the new Artificial Joints not only offers longevity to the joint prostheses but also gives a near-natural movement feel to patients.
  • Minimally Invasive Joint Replacement Surgeries provide a faster recovery to the patient and also reduce the risk of infections or failure of the new Joint, thereby significantly reducing the risk of a Revision Joint Replacement Surgery.

Best Robotic Knee Replacement in India for International Patients.

Best Robotic Hip Replacement in India for Foreign Patients.


Availability of the Best Original Imported Artificial Joints in India

All the leading original Imported implants from the World Leaders in Joint Prostheses are available in India. The Quality of Implants plays an important role in the success, longevity, and reducing the risk of a Revision Joint Replacement Surgery. The Top Joint replacement Prostheses available in India are:
  • Stryker
  • Johnson & Johnson
  • Zimmer Biomet
  • Smith & Nephew
  • Max Merill & Heraeus

Comparison of Joint Replacement cost in India and other countries

The Joint Replacement Cost in India is probably the Lowest in the World. The Joint Replacement Costs at Major Medical tourism countries for Foreign patients are mentioned below:

Knee Joint Replacement Costs

Spain

Average Unilateral Total Knee Replacement Cost: Approx. 12'600 - 25'200 USD

Poland

Average Unilateral TKR Cost: Approx. 7500 - 17500 USD

India

Cost of investigations ( X-ray, MRI, Blood tests, etc.) Approx. 200 - 400 USD
Unilateral Total Knee replacement cost  (Single Knee)Approx. 4500 - 5900 USD
Bilateral Total Knee Replacement (for both Knees)Approx. 7400 - 9000 USD
Robotic Knee replacement costApprox. 5500 - 6500 USD
One-step revision knee replacement costApprox. 8000 - 9000 USD
Two-step revision knee replacement costApprox. 10'000 - 12'000 USD

Singapore

Average Unilateral TKR cost in Singapore: Approx. 19000 to 45000 USD

Thailand

Average Unilateral Total Knee Replacement Cost in Thailand: Approx. 9500 - 11600 USD

Turkey

Average Unilateral Total Knee Replacement Cost: Approx. 7000 to 16000 USD

Hip Joint Replacement Cost 

Spain

Average Unilateral Total Hip Replacement Cost: Approx. 17'600 - 25'200 USD

Poland

Average Unilateral Hip Replacement Cost: Approx. 9500 - 17500 USD

India

Hip replacement workup cost (X-ray, MRI, cardiac evaluation, blood tests, etc.)Approx. 400 USD - 600 USD
      Unilateral Partial Hip Replacement Cost Approx. 4500 USD - 5500 USD
      Unilateral Total Hip Replacement CostApprox. 5500 USD - 7500 USD
Bilateral Hip replacement CostApprox. 8000 USD - 12000 USD
 Revision Hip Replacement costApprox. 9000 USD -11000 USD

Singapore

Average Unilateral Hip Joint Replacement Cost in Singapore: Approx. 19000 to 45000 USD

Thailand

Average Unilateral Total Hip Replacement Cost in Thailand: Approx. 10'500 - 12600 USD

Turkey

Average Unilateral Total Hip Replacement Cost: Approx. 12'000 to 16000 USD

The Other related logistics Cost for Foreigners

The other related logistics Costs like guest houses and budget hotels, local transportation, and other costs are also probably the lowest in India as compared to other countries. It results in significant money saving for foreign patients seeking Knee Joint and Hip Joint Replacement Surgery outside their countries.








Rehabilitation plays an important role in early movement and recovery after Joint Replacement surgery. CMCS Health, the Best Medical Tourism company in India for Foreign Patients is associated with the Best Indian Hospitals and Orthopaedic surgeons with well-experienced physiotherapists for our global guests.

The Name Trusted by International Patients for Knee Joint and Hip Joint Replacement Surgery.





Sunday, 3 December 2017

Complications of Diabetes- Diabetic Nephropathy.

Medical Treatments in India with Best Doctors in Best Indian Hospitals.

Complications of Diabetes- Diabetic Nephropathy.

Awareness is the THE LIGHT that keeps away the darkness of many sufferings.

At CMCS Health we have devoted ourselves for ensuring good health and best specialized medical treatment for all.We do believe that prevention is better than cure.In continuation of our efforts of 
ensuring good health we try to create awareness and arrange and
 coordinate best and cost effective specialized medical treatment for the sufferer in India with best Indian specialist doctors and best and well equipped and well managed hospitals.
Diabetes is not just one disease,it gives rise to many health problems. We are starting this awareness series about complications of diabetes associated health problems.
We have discussed earlier diabetes induced retinopathy.
In this blog we are highlighting another Diabetes Induced complication that is diabetic nephropathy.
The word Nephropathy indicates Kidney disease. Diabetic nephropathy means onset of kidney disease because of diabetes.
If untreated diabetic nephropathy can lead to irriversible kidney damage and ultimately kidney failure.